In spay incontinence, the dog doesn’t seem to know when she needs to pee.  This can be frustrating and messy.  A number of medications have been used to control the problem, some with fewer side effects than others.

The most obvious med to use is a hormone replacement called stilbestrol.  This is a pink pill with a sugar coating that can be cut into sections if your dog becomes nauseated after swallowing a whole pill.  It’s usually effective, but if there’s been any nerve damage the results may vary.

Another popular remedy is ephedrine.  This is the drug that makes people “pee like a racehorse”.  Athletes have used it to enhance their energy level, so of course it can make a dog hyper.  It can even cause hallucinations when used over time.  If you have a dog that is nervous during thunderstorms, ephedrine will make things worse and the dog may not be happy taking this medication. Moreover, the pill has a bitter taste that makes the dog want to spit it out.

Other options are Sudafed and phenylpropanolamine (PPA), which have worked well for some.

There are herbal remedies like cornsilk that have worked for some, and others find that eliminating grains from the diet works for some dogs.  You may have to experiment and take precautions in the meantime.  Diapers for dogs are available, and mattress pads with a plastic lining can be found.  Even something like a plastic table covering can be placed under the washable cover of a dog bed.

Probably the best course of action is to join a newsgroup for your breed and find out what others have tried and the dosage range for your breed and size of dog. Of course, consult your vet after doing your research.